Plasma vs Tissue Genotyping: Debate
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Physicians who wish to advance their current knowledge of the advantages and limitations of using tumor tissue as a sample source for genotyping.
- Understand the key nuances of genomic reports.
- Effectively integrate cell-free DNA profiling and clinical decision-making.
- Identify genomic markers of response and resistance.
- Understand the advantages and limitation of using tumor tissue as a sample source for genotyping.
Accreditation and Credit Designation
The Society for Translational Oncology is accredited by the ACCME to provide continuing medical education for physicians.
The Society for Translational Oncology designates this journal-based CME activity for a maximum of 0.5 AMA PRA Category 1 Credit™. Physicians should only claim credit commensurate with the extent of their participation in the activity.
It is the policy of the Society for Translational Oncology (STO) to ensure balance, independence, objectivity, and scientific rigor in all of its educational activities through the disclosure of financial interests and other relationships. As an education provider accredited by the Accreditation Council for Continuing Medical Education (ACCME), STO must comply with the ACCME Standards for Integrity and Independence.
In accordance with the policy of STO, all persons in a position to control the content of a CME activity must disclose any financial relationships with ineligible companies occurring within the last 24 months. STO abides by a policy of anonymous peer review: disclosure of any financial relationships with ineligible companies/commercial interests will be reviewed by the CME Activity Directors with the ad hoc assistance of external reviewers; any conflicts of interest found will be mitigated prior to the activity.
Author Disclosure(s)A. John Iafrate, M.D.
- Consulting fees: Abbvie, Array Biopharma/Pfizer, Asana Biosciences, Astex Pharmaceuticals, Avidity Biosciences, BMS, C4 Therapeutics, Elicio, Erasca, Fog Pharma, Guardant Health, Ipsen, Kinnate Biopharma, Mirati Therapeutics, Natera, Navire, N-of-one/Qiagen, Novartis (last 2019), nRichDx, Remix Therapeutics, Revolution Medicines, Roivant, Shionogi (last 2019), Taiho, Tango Therapeutics, Zikani Therapeutics
- Speaking honoraria: AstraZeneca, Guardant Health
- Scientific Advisory Board/Equity Holder: Avidity Biosciences, C4 Therapeutics, Erasca, Kinnate Biopharma, nRichDx, Remix Therapeutics, and Revolution Medicines
- Research Funding: Asana (ended 2019), AstraZeneca (ended 2019), Lilly, and Novartis
Bruce Chabner, M.D.
EMD Serono, Cyteir, Eli Lilly & Co., Boston Pharmaceuticals, Chugai Pharmaceuticals.
Aditya Bardia, M.D., MPH
Advisory role with Pfizer, Novartis, Genentech, Merck, Radius Health, Immunomedics, Taiho, Sanofi, Diiachi Pharma/Astra Zeneca, Puma Biotechnology, Biothernostics Inc., Phillips, Eli Lilly, Foundation Medicine.
Research funding from BGenentech, Novartis, Pfizer, Merck, Sanofi, Radius Health, Immunomedics, Diiachi Pharma/Astra Zeneca.
CME Program Editor Disclosures
Jayne S. Gurtler, M.D., F.A.C.P.
No financial relationships relevant to the content of this activity have been disclosed.
Staff Planners Disclosures
No financial relationships relevant to the content of this actvity have been disclosed by the staff planners.
This activity was funded in part through educational grants from Novartis Pharmaceuticals Corp. and Regeneron Pharmaceuticals, Inc and Sanofi Genzyme.
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